David West had 15 points and seven rebounds and George Hill added 15 points and eight assists to help the Pacers to their fourth straight victory overall and their longest home win streak in 13 years.
Jeff Teague had 24 points and eight assists and Al Horford had 15 points and eight rebounds to lead the Hawks, who have lost three of their last four.
The Pacers went on a 7-2 run midway through the fourth quarter.
Lance Stephenson scored on a layup before Hill hit a 3-pointer with 6:28 left to play to give the Pacers a 100-84 lead, their largest advantage of the game.
George made two free throws to give the Pacers a 93-80 lead before Johan Petro scored for Atlanta.
Then George scored two more free throws to put the Pacers up 13 again with 7:17 left to play.
The Pacers then pulled away for good when Hill’s 3 gave Indiana its 16-point lead.
George hit a 3 with 2:39 left in the third quarter to put the Pacers up 75-67.
The Hawks missed a layup and D.J. Augustin, who had 10 points, drove to the basket and the officials spend eight minutes reviewing the play to determine that Horford committed a flagrant foul on the play and Augustin was called for a technical.
Augustin scored two free throws and John Jenkins scored the technical free throw to give the Pacers a 79-68 lead.
The Pacers led 81-70 at the end of the third quarter.
Teague dunked off a steal at the start of the fourth quarter and George answered with a 3 to extend the lead again and Mike Scott scored on a putback to make it 84-76.
Later, Stephenson hit a 3 to give the Pacers an 89-78 lead with 9:20 left in the game.
After the Hawks jumped out to a 7-3 lead, the Pacers scored the next eight points.
Hibbert scored in the paint and later hit a jumper.
Then when George missed a jumper, Hibbert grabbed the rebound and passed it under the basket to George, who scored on a reverse dunk to give the Pacers the 11-7 lead with 6:56 left in the first quarter.
Kyle Korver’s 3 gave the Hawks a 43-31 lead with 5:15 left in the second quarter.
The Pacers then went on an 13-2 run. Stephenson scored a layup and later a 3, and Hill made two free throws and a jumper.
Stephenson scored two more free throws to pull Indiana to 45-44 with 2:48 left in the second quarter.
Later, Hill made 1 of 2 from the line to tie the score at 47.
The Hawks missed a shot and then George hit a 3 to give the Pacers a 50-47 lead with 1:10 left in the first half.
The Pacers led 50-49 at halftime.
NOTES: Teague returned to his hometown where he graduated from Pike High School in Indianapolis. ... Korver tied Clifford Robinson for 33rd on the league’s all-time 3-pointers made list after going 2 of 9 against the Pacers.